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生产厂家厂商性质
台州市所在地
中文名称: | 棘白菌素B |
中文同义词: | 棘球白素(伊曲康唑) B;棘白菌素;阿尼芬净中间体;棘球白素;棘白菌素 B;棘球白素 B;棘白菌素B0;ECHINOCANDIN B0棘白菌素B0 |
英文名称: | ECHINOCANDIN B |
英文同义词: | Echinocandin B;B Echinocandin B;antibiotic a-30912a nucleus;Echinocandin B,1-[(4R,5R)-4,5-dihydroxy-L-ornithine]- (9CI);1-((4r,5r)-4,5-dihydroxy-l-ornithine)echinocandin b;Echinocandin B0 |
物化性质:
密度:1.6
沸点:1330.8ºC at 760 mmHg
闪点:758.6ºC
折射率:1.689
Echinocandin B, a lipopeptide, is a naturally occurring cyclic hexapeptide with a linoleoyl side chain. It belongs to a class of antifungal agents called echinocandins, which inhibits the synthesis of glucan, a major component of the fungal cell wall, via noncompetitive inhibition of a crucial enzyme, β-(1,3)-D-glucan synthase. Echinocandin B is a fermentation product of Aspergillus nidulans and the closely related species, A. rugulosus; discovered in 1974 in A. nidulans var. echinulatus strain A 32204 in Germany, it was the first of the echinocandin class of antifungals.