全自动灭菌发酵罐
Automatic sterilization fermentation tank
概 述：工作体积15L,本发酵系统的材质、结构、布局按照发酵系统设计，符合GMP标准。本系统配有所需的补料瓶、蠕动泵、循环泵、控制阀、管路系统、控制系统，充分保证系统的安全性、可靠性；还可配置空气、蒸汽和水的预处理系统，在完成安装调试后，只需接入蒸汽、空气、水源和电源就可进行发酵运行。
罐体结构：主体材质为全不锈钢，罐内；带发酵罐专用取样、放料阀，移种管道。采用大视角罐内液位观察
视镜，12V安全视灯，带有液位接口、接种口、补料口、及多个备用口，所有焊缝坚固整齐美观。罐体及夹套的设计压力均为0.3Mpa，采用优化导流设计，提高了交换效率和罐内温度的均匀性，温度的控制稳定均匀
是发酵得以成功的基本条件。
表面处理：内外抛光，且容易清洗，精度：0.4um。
灭菌方式：自动程序灭菌，灭菌过程可编程控制；可设置灭菌顺序，范围：100℃~130℃，气动阀通过程序控制进行高温灭菌。对于有些发酵品种对灭菌温度要求波动很小,可降低劳动强度的可以选用自动程序控制灭菌，此时灭菌温度非常精确
搅拌系统：采用直接耦合机械搅拌和罐顶式机械密封系统，以及英国机械密封(约翰克兰)、高性能搅拌桨、消泡桨、交流调速电机，无级调速机, 可进行全自动控制。大功率的变速机构使搅拌稳定可保持运转自如且不需要添加润滑油，全自动设定控制范围50～1000 rpm；
温度自动控制系统：进水经过补水阀；电加热，水冷却，超温保护功能，LCD触摸屏控制；循环水加热和冷却系统；范围：冷却水温度5~65℃；精度：±0.2℃；分辨率：0.01℃，配套制冷循环装置，具有良好的热交换效率；智能PID控制既保证了温控的快速性又实现了节能。发酵温度控制范围：冷却水温度5~65℃, 精度：±0.1℃，温度的精度和稳定对发酵的结果有着决定性的影响。
流量检测与压力检测系统：转子流量计检测,手动控制空气流量
pH自动控制：检测pH，采用智能PID控制，蠕动泵自动添加酸、碱，精确控制pH（有手动、关闭、自动三档可切换）。显示范围：0.00~14.00±0.01，全自动控制范围：2.00~12.00±0.05。控制器可实现：pH值曲线分析、加酸、加碱量曲线分析、批报表分析、酸加入量累计显示记录、碱加入量累计显示记录、数据保存
DO在线检测：可通过转速、补料等进行联动控制。智能PID控制，使溶解氧这个以往较难控制的参数，也达到了很理想的控制效果。控制范围：0~150%±1%, 控制器可实现：DO值曲线分析、批报表分析（根据发酵时间，DO自动变量控制，至少10段）。
补料控制：具备完善的补料系统，补料可计量，可曲线记录；蠕动泵数量可根据需要选择，常规配置为每台发酵罐二个。蠕动泵的作用可在控制界面上选择设定，这样使用户在实际使用时更为方便灵活。配有特别设计的补料插针，以确保补料的安全操作。
Overview:Work volume of 15L, the material, structure and layout of the fermentation system are in full accordance with the fermentation system design, conforming to GMP standards.This system is equipped with required fill liu bottles, wriggle pump, circulating pump, the control valve and pipe system, control system, fully guarantee system of safety, reliability,configure pretreatment system of air, steam and water in complete installation debugging, after only access steam, air, water, and power source can be fermented operation.
Tank structure: Main material as a whole stainless steel, with no dead angle. Take special sampling, pick feeding valve, and the moveing microorganism pipeline. Adopted of observing endoscopic of big angle with tank level, safety depending on the lamp of 12V, with liquid level interface, vaccination mouth, filling material mouth, and multiple alternate mouth, all welds fortified tidy and beautiful. The design pressure of tanks and clip set are 0.3 Mpa, adopting the optimization diversion design, improved exchange efficiency and tank temperature uniformity,temperature control stability uniform is the basic conditions of fermentation to be successful.
Surface treatment: Internal and external polishing and easy cleaning, precision: 0.4um.
Sterilization mode: Automatic procedure sterilization, sterilization process programmable control. Can install sterilization sequence, the scope: 100 ℃ 130 ℃, pneumatic valve through procedure control on high temperature sterilizing. For some fermentation varieties to sterilization temperature requirements fluctuation, then reduce the labor intensity can choose automatic procedure control sterilization, now sterilization temperature is very precise.
Mixing system: Adopt direct coupling mechanical agitation and pot type mechanical seal system, ａnd the British mechanical seal (John crowe LAN), high-performance agitator, defoaming OARS, exchange control motor, stepless speed regulation machine, can undertake full automatic control. High power shifting institutions make mixing stability can keep running freely, ａnd do not need to add lubricating oil, automatic setting control range is of 50～1000rpm.
Automatic temperature control system:after filling water inlet valve. Electrical heating water cooling, overtemperature protection function, LCD touch screen control. Circulating water heating and cooling system. Scope: cooling water temperature of 5～65℃. Precision: ±0.2℃.Resolution: 0.01℃, supporting refrigeration device, with good heat efficiency. Intelligent PID control not only ensure the temperature control of the output and can save energy. The fermentation temperature control scope: The temperature of the cooling water 5～65 ℃,precision: ±0.1℃，the precision and stability of temperature of fermentation has a decisive influence on the result.
Flow test and stress test system: Rotor flowmeter test, manual control air flow.
PH automatic control: Detection pH, using intelligent PID control, wriggle pump automatically add acid, alkali, precise control pH (with manual and closed, automatic three gears can switch).Display range: 0.00～14.00±0.01，automatic control scope: 2.00～12.00±0.05. Controller can realize: PH value curve analysis, plus acid, add alkali amount curve analysis, batch statement analysis, acid addition amount accumulative total registering, alkali addition amount accumulative total display records, data storage.
DO online testing: By rotation speed, filling material for linkage control. Intelligent PID control, make this ever more difficult to control of dissolved parameters, also achieved very good controlling effect. Control scope: 0～150%±1%, Controller can realize: DO value curve analysis, batch statement analysis (according to fermentation time, DO automatic variables, control, at least 10 section).
Filling material control: With perfect fill material system, filling material will measure, can curve record. Peristaltic pump quantity can be choosed according to need. Conventional configured for each machine pick with two peristaltic pump.
The role of peristaltic pump can be selected in the control interface, so that the user in actual use is more convenient. Equipped with special design of filling material insert needle, to ensure the safe operation of filling material.
