盐酸山梗碱，盐酸洛贝林，山梗烷醇酮盐酸盐原料药的研发进程
时间：2023-08-30 阅读：412
| 中文名 | 盐酸山梗碱 |
| 英文名 | (-)-Lobeline Hydrochloride |
| 别名 | 盐酸洛贝林 盐酸山梗碱 洛贝林盐酸盐 山梗菜碱盐酸盐 山梗烷醇酮盐酸盐 Α-洛贝林盐酸盐 盐酸-L-山梗碱 (-)-洛贝林 盐酸盐 2-[1-甲基-6-(beta-羟基苯乙基)-2-哌啶基]苯乙酮盐酸盐 2-[6-(2-羟基-2-苯乙基)-1-甲基-2-呱啶基]-1-苯乙酮 盐酸盐 |
| 英文别名 | (-)-id Lobeline HCL Lobelinhydrochloride Lobelin Hydrochlorde Lobeline hydrochloride (-)-Lobeline Hydrochloride alpha-Lobeline hydrochloride butane-1,4-diyl dimethanesulfonate 2-[6-(2-HYDROXY-2-PHENETHYL)-1-METHYL-2-PIPERIDYL]ACETOPHENONE HCL 2-(6-(beta-hydroxyphenethyl)-1-methyl-2-piperidyl)-acetophenonhydrochlor 2-(6-(2-hydroxy-2-phenethyl)-1-methyl-2-piperidyl)acetophenone hydrochloride 2-((2R,6S)-6-((S)-2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone 2-[6-(.beta.-hydroxyphenethyl)-1-methyl-2-piperidyl]-,hydrochloride,(-)-Acetophenone 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone 2-(6-[2-HYDROXY-2-PHENYLETHYL]-1-METHYL-2-PIPERIDINYL)-1-PHENYLETHANONE HYDROCHLORIDE 2-((2R,6S)-6-((S)-2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl)-1-Phenylethanone Hydrochloride 2-{(2R,6S)-6-[(2R)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride |
| CAS | 134-63-4 |
| EINECS | 205-150-2 |
| 化学式 | C22H28ClNO2 |
| 分子量 | 373.92 |
| InChI | InChI=1/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21+;/m0./s1 |
| 熔点 | 183-185°C (dec.)(lit.) |
| 沸点 | 510.5°C at 760 mmHg |
| 比旋光度 | D20 -43° (c = 2) |
| 闪点 | 262.5°C |
| 蒸汽压 | 3.02E-11mmHg at 25°C |
| 溶解度 | H2O: 25mg/mL |
| 折射率 | -57.5 ° (C=1, H2O) |
| 存储条件 | Inert atmosphere,Room Temperature |
| 外观 | powder |
| 颜色 | white to off-white |
| Merck | 14,5551 |
| BRN | 3920196 |
