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Versatile: Safeguards endogenous fluorescence, protein antigenicity, nucleic acids, and overall tissue architecture. Synergizes with a range of existing tissue processing approaches including SWITCH (Cell, 2015) and MAP (NBT, 2016).
Easy & Reliable: Superior tissue preservation vs. CLARITY, without the variability of hydrogel embedding. Compatible with both non-fixed and PFA-fixed tissues.
Fast: Streamlined protocol preserves samples in a matter of days with minimal steps.
Repeated Staining & Imaging: Protects tissue during FP-imaging and antibody labeling across individual rounds.
Available in 250mL and 500mL Kits
SHIELD Epoxy
SHIELD Buffer
SHIELD ON
250mL kit is for 8 mouse brains or samples of equivalent size
500mL kit is for 16 mouse brains or samples of equivalent size
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