生物发酵罐由发酵罐，空气处理系统、蒸汽净化系统、电器控制系统、恒温系统及管路、阀门、辅助系统，传感器与一次仪表系统，下位机控制系统（现场PLC控制系统，二次仪表），上位机系统以及台架等组成。生物发酵罐厂家
生物发酵罐厂家Biological Fermentor
发酵罐概述Overview Of Fermentation Tank
常见的发酵罐分为固体发酵罐和液体发酵罐。发酵罐根据容积和用途不同，分为种子罐（菌种发酵罐）和发酵罐。发酵罐根据需氧类型的不同又分为通风式发酵罐和厌氧发酵罐。发酵罐、种子罐，有碳钢制、不锈钢、高镍基合金等，主要用于生化发酵生产。如生产味精、柠檬酸、酶制剂、溶剂、制药、食品等行业。
Common fermentation tanks are divided into solid fermentation tank and liquid fermentation tank. Fermentation tank is divided into seed tank (strain fermentation tank) and fermentation tank according to different volume and purpose. According to different aerobic types, fermentation tanks are divided into ventilated fermentation tanks and anaerobic fermentation tanks. Fermentation tank and seed tank, made of carbon steel, stainless steel and high nickel base alloy, are mainly used for biochemical fermentation production. Such as monosodium glutamate, citric acid, enzyme preparation, solvent, pharmaceutical, food and other industries.
一、发酵罐的基本条件Basic Conditions Of Fermentation Tank
机械搅拌发酵罐是发酵工厂常用类型之一。它是利用机械搅拌器的作用，使空气和醪液充分混合，促使氧在醪液中溶解，以保证供给微生物生长繁殖、发酵所需要的氧气。使用发酵罐的基本要求：
Mechanical stirring fermentor is one of the commonly used types in fermentation plants. It uses the function of mechanical stirrer to fully mix air and mash, and promote the dissolution of oxygen in mash, so as to ensure the supply of oxygen required for microbial growth, reproduction and fermentation. Basic requirements for using fermentor:
1、发酵罐应具有适宜的径高比。发酵罐的高度与直径之比一般为1.7~4倍左右，罐身越长，氧的利用率较高。
2、发酵罐能承受一定压力。由于发酵罐在消毒及正常工作时，罐内有一定的压力（气压与液压）和温度，因此罐体各部件要有一定的强度，能承受一定的压力。
3、发酵罐的搅拌通风装置使气液充分混合，保证发酵液必须的溶解氧。
4、发酵罐应具有足够的冷却面积。微生物生长代谢过程放出大量的热量，为了控制发酵过程不同阶段所需的温度，应装有足够的冷却面积。
5、发酵罐内应尽量减少死角，避免藏垢积污，易灭菌，避免染菌。
6、搅拌器的轴封应严密，尽量减少泄漏。
(1) The fermentation tank shall have appropriate diameter height ratio. The ratio of height to diameter of fermentation tank is generally about 1.7 ~ 4 times. The longer the tank body, the higher the utilization rate of oxygen.
(2) The fermentation tank can withstand certain pressure. Since there is a certain pressure (air pressure and hydraulic pressure) and temperature in the fermentation tank during disinfection and normal operation, all parts of the tank must have a certain strength and can withstand a certain pressure.
(3) The stirring and ventilation device of the fermentation tank can fully mix the gas and liquid to ensure the dissolved oxygen of the fermentation broth.
(4) The fermentation tank shall have sufficient cooling area. Microbial growth and metabolism process releases a lot of heat. In order to control the temperature required in different stages of fermentation process, sufficient cooling area should be installed.
(5) The dead corner shall be minimized in the fermentation tank to avoid dirt accumulation. The sterilization can be complete and bacteria contamination can be avoided.
(6) The shaft seal of the mixer shall be tight to minimize leakage.
二、发酵罐罐体尺寸比例Size Proportion Of Fermentation Tank
罐体各部分的尺寸有一定的比例，罐的高度与直径之比一般为1.7~4倍左右。
发酵罐通常装有两组搅拌器，两组搅拌器的间距S约为搅拌器直径的三倍。
对于大型发酵罐以及液体深度HL较高的，可安装三组或三组以上的搅拌器。
最下面一组搅拌器通常与风管出口较接近为好，与罐底的距离C一般等于搅拌器直径Di，但也不宜小于0.8Di，否则会影响液体的循环。
The size of each part of the tank body has a certain proportion, and the ratio of tank height to diameter is generally about 1.7 ~ 4 times.
The fermentation tank is usually equipped with two groups of agitators, and the spacing S between the two groups of agitators is about three times the diameter of the agitator.
For large fermentation tanks and those with high liquid depth HL, three or more groups of agitators can be installed.
The bottom group of agitators is usually close to the outlet of the air duct. The distance C from the tank bottom is generally equal to the agitator diameter Di, but it should not be less than 0.8di, otherwise the liquid circulation will be affected.
三、发酵罐的结构Structure Of Fermentation Tank
好气性机械搅拌发酵罐是密封式受压设备，主要部件包括罐身、搅拌器、轴封、打泡器、联轴器、中间轴承、空气吹泡管（或空气喷射器）、挡板、冷却装置、人孔以及管路等。
系统由发酵罐，空气处理系统、蒸汽净化系统、电器控制系统、恒温系统及管路、阀门、辅助系统，传感器与一次仪表系统，下位机控制系统（现场PLC控制系统，二次仪表），上位机系统以及台架等组成。
Aerobic mechanical stirring fermentation tank is a sealed pressure equipment, and its main components include tank body, agitator, shaft seal, bubbler, coupling, intermediate bearing, air bubbling pipe (or air ejector), baffle, cooling device, manhole and pipeline.
The system is composed of fermentation tank, air treatment system, steam purification system, electrical control system, thermostatic system and pipeline, valve, auxiliary system, sensor and primary instrument system, lower computer control system (field PLC control system, secondary instrument), upper computer system and bench.
四、生物发酵罐厂家技术参数/Technical Parameter
| 公称体积 Nominal Volume | 5~3000L |
| 装液系数Liquid Loading Coefficient | 65-80%, Optimum 70% |
| 罐体配置 Can Body Configuration | 不锈钢SUS316L/SUS304材质； Stainless steel SUS316L / SUS304 Material; Jacket temperature control and optimization of diversion design; Internal surface polishing, RA ≤ 0.6 μ m； External surface polishing or matte treatment (glass shot blasting); Long strip mirror with large viewing angle, complete interfaces of pH electrode, do electrode and temperature electrode; The tank cover is equipped with flame inoculation port and feeding standby interface, etc |
| 搅拌系统 Mixing System | 顶入式机械搅拌系统；无菌机封系统；直流搅拌电机（10L及以下）或交流电机； Jacking mechanical mixing system; Aseptic mechanical sealing system; DC mixing motor (10L and below) or AC motor; Standard configuration: 2-layer flat impeller and one-stage high-efficiency defoaming paddle; There are also inclined blades, curved blades, axial flow blades, etc; Adjustable speed, digital setting speed control |
| 结构方式 Structure Mode | 落地式框架结构，节省空间，万向脚轮，操作方便 Floor type frame structure, space saving, universal casters, convenient operation |
| 通气系统Ventilation System | 深层通气，全不锈钢管路； Deep ventilation, all stainless steel pipeline; Glass rotor flowmeter display, pressure display, manual valve adjustment flow; High efficiency sterilizing filter equipped with stainless steel housing, with a filtration accuracy of 0.01 μ m； External compressed air is required, equipped with high-quality water removal and pressure stabilizing devices, to continuously and stably supply gas; Optional mass flow controller for automatic control of air flow |
| 罐压控制 Tank Pressure Control | 顶部排气口配置指针式压力表显示罐压，不锈钢阀门手动调节； The top exhaust port is equipped with a pointer pressure gauge to display the tank pressure, and the stainless steel valve is manually adjusted; It can be equipped with inlet pressure transmitter and automatic regulating valve to realize automatic control of tank pressure |
| 温度控制/Temperature Control | 在线检测，数字化设定，自动/手动控制自由切换； Online detection, digital setting, automatic / manual control, free switching; German PT-100 temperature probe and digital temperature instrument; Automatic temperature control of electric heating thermostatic water tank and external cooling water |
| Ph控制 Ph Control | 在线检测，1路或2路蠕动泵自动流加碱或酸液进行调节； Online detection, 1 or 2 peristaltic pumps automatically add alkali or acid for regulation; Imported Mettler (Hamilton) pH electrode, which can be sterilized by high temperature steam |
| 溶氧(Do) Dissolved Oxygen (Do) | 在线检测，范围0-100%或0-200%； Online detection, range 0-100% or 0-200%; Imported Mettler (Hamilton) do electrode, which can be sterilized by high temperature steam; Optional linkage control with speed and ventilation (to be specified when ordering) |
| 补料控制Replenishment Control | 标配1路/2路等多路蠕动泵时间比例流加补料，流加量累积显示、记录 It is equipped with 1-way / 2-way and other multi-channel peristaltic pumps as standard, with time proportional flow feeding and feeding, and the cumulative flow feeding amount is displayed and recorded |
| 消泡方式Defoaming Mode | 传导式泡沫电极，泡沫异常状况自动报警； The conductive foam electrode automatically alarm the abnormal condition of foam. One peristaltic pump is equipped as standard for automatic / manual flow of defoamer, and the cumulative flow dosage is displayed and recorded |
| 控制系统 Control System | 应用工业级MC-bio控制系统，采用西门子PLC控制器； Apply industrial MC bio control system and Siemens PLC controller; 32-bit true color touch screen operation interface with complete functions and stable operation; Another type a simple instrument control system is optional |
| 灭菌方式/Sterilization Method | 在位灭菌，手动控制，需接外源饱和蒸汽 In place sterilization, manual control, need to connect external saturated steam |
| 可选配项/Optional Configuration | 1.多路补料 Multiple feeding |
| 设备特点Equipment Characteristics | 在位灭菌，安全可靠，培养基浓度准确； In situ sterilization, safe and reliable, accurate medium concentration; No risk of transmission leakage; Large viewing angle longitudinal mirror observation is clear; Various and reliable inoculation methods (standard flame inoculation port, differential pressure inoculation port and other forms are optional); Floor type tank, beautiful and generous; Easy operation and disassembly; Special specifications can be customized. |
